Impact of intra-operative cell salvage on blood coagulation in high-bleeding-risk patients undergoing cardiac surgery with cardiopulmonary bypass: a prospective randomized and controlled trial

Table 1 Inclusion and exclusion criteria of patients

	Inclusion criteria	Exclusion criteria
Opportunity of surgery	Scheduled for cardiac surgery with CPB	Emergency cardiac surgery with CPB
Type of surgery	Multiple valves replacement	The first time single valve replacement
	Bentall
	Reoperation (at least 1 item above 3 items must be met)
Characteristics of patient	Age >70 years
	BSA <1.6 m²
	Cr >15 mg/L
	Liver Child–Pugh B or C
	R (TEG) >10 min;
	HB <13 g/dL (male) or 12 g/dL (female)
	PLT <50 × 10⁹/L
	Drug withdrawal <3 days (Aspirin) or 7 days (Clopidogrel) (at least 2 items above 8 items must be met)

Eligible patient must meet opportunity of surgery and type of surgery and characteristics of patient at the same time
Multiple valves replacement aortic valves replacement + mitral valve replacement
Bentall aortic valve replacement + ascending aorta and aortic root replacement
Reoperation not the first time single or multiple valve replacement
BSA body surface area, TEG thromboelastography, HB hemoglobin, PLT platelets, Cr creatinine

ISSN: 1479-5876