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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Production of functional, stable, unmutated recombinant human papillomavirus E6 oncoprotein: implications for HPV-tumor diagnosis and therapy

Fig. 7

Anti-E6 humoral responses in mice. Mice were inoculated with 20 µg purified HPV16 His6-E6 protein (100 µL) produced under denaturing or native conditions in Freund incomplete (FrInc) or MF59 adjuvants, and with the control of the adjuvants alone (as indicated). Sera were collected 1 week after last boost immunization, pooled and analyzed by ELISA for the levels of E6-specific antibodies. ***p < 0.001 vs. denatured protein/control inoculation

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