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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: A short CD3/CD28 costimulation combined with IL-21 enhance the generation of human memory stem T cells for adoptive immunotherapy

Fig. 2

Short CD3/CD28 costimulation increases CD4+ and CD8+ TSCM frequencies compared with long costimulation. Naïve T cells from healthy donors (n = 6) were cultured for 10 days with short (48 h) (solid black line) or long (solid grey line) costimulation. a, b Frequency of CD4+ (a) and CD8+ (b) TSCM cell subset (mean ± SEM). c, d Frequencies of total TSCM (TSCM + TSCM-like) CD4+ (c) and CD8+ (d) (mean ± SEM). *p < 0.05; **p < 0.01; ***p < 0.001

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