Fig. 7

Representative fluorographs (A) and quantitative analysis of reactive oxygen species production in transverse sections of aorta (B) evaluated by the ethidium-bromide-positive nuclei under basal conditions and after incubation with apocynin (30 mM), or with Mn(III) tetrakis1-methyl-4-pyridyl porphyrin pentachloride (MnTMPyP, 25 µM). Bar scale 100 μm. Sedentary and exercised (Ex) wild-type (WT) and LDLr knockout mice (LDLr^−/−). Data are mean ± SEM (n = 4–15 per group). 2-way ANOVA: * p < 0.05 vs. WT S; ^# p < 0.05 vs. LDLr^−/− S; + p < 0.05 apocynin vs. basal