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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk

Fig. 3

MACC1 transcripts in normal, hyperplastic (HPP) and tubular adenoma (TA) patients’ plasma. a MACC1 transcripts were detected in all measured normal (n = 45), HPP (n = 15) and TA (n = 33) patients’ plasma. MACC1 transcript levels were higher in all adenoma patients’ plasma (median 0.6036 MACC1 mRNA expression/percent calibrator) vs. normal patients’ plasma (median 0.4315 MACC1 mRNA expression/percent calibrator; p = 0.014). MACC1 transcript levels were also higher in TA patients plasma (median 0.6045 MACC1 mRNA expression/percent calibrator) vs. normal patients’ plasma (p = 0.011). However, MACC1 transcript levels were not significantly higher in HPP patients plasma (median 0.5788 MACC1 mRNA expression/percent calibrator) vs. normal patients’ plasma (p = 0.239). b Area under the curve was calculated for the diagnostic value of plasma MACC1 transcripts for Normal vs. HPP, Normal vs. Adenoma and for Normal vs. Adenoma/HPP combined

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