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Table 3 Various non-hotspot BRAF mutations identified in four out of 204 cases of adult DTC

From: Classical V600E and other non-hotspot BRAF mutations in adult differentiated thyroid cancer

Tumor no

Sex

Histology

Exon

Nucleotide

Codon

Amino acid

Mutation

Status

AZ 274

F

FV-PTC

15

C1796T

ACA-ATA

T599I

Missense

Heterozygous

AZ 152

F

FV-PTC

15

1798inTAC

 

T599dup

Insertion

In frame

AZ 40

F

CPTC

15

A1801G

AAA-GAA

K601E

Missense

Heterozygous

AZ 172

F

FV-PTC

15

A1801G

AAA-GAA

K601E

Missense

Heterozygous

  1. F female; FV-PTC follicular variant papillary thyroid cancer; CPTC conventional papillary thyroid cancer