Fig. 1

Identification of BRAF mutations in adult differentiated thyroid cancer. a The chromatogram shows a rare, somatic, non-hotspot, insertion mutation of BRAF gene in exon 15 at nucleotide position 1798 [1798insTAC (T599dup)]. b Shows a rare, somatic, non-hotspot, point mutation of BRAF gene in exon 15 at nucleotide position 1796 [C1796T (T599I)]. c A representative sequencing results shows a rare, somatic, non-hot spot, point mutation of BRAF gene in exon 15 at nucleotide position 1801 [A1801G (K601E)] from two independent tumor samples. In all the above cases, sequencing results of the matched normal tissue of each sample are shown in the left side of the panel. All the samples were repeated by independent PCR reactions with forward and reversed sequencing