Fig. 1

DBR supplementation reduces LDL cholesterol and increases hdl cholesterol in a mouse model of hypercholesterolemia. Three groups of mice were evaluated for cholesterol concentrations in serum obtained from peripheral blood (PB) or by cardiac puncture. The groups were as follows: (1) Control mice maintained on a low fat diet; (2) Control mice maintained on a high fat diet; and, (3) Experimental mice maintained on a high fat diet and supplemented with DBR in their drinking water. Analyses of LDL (a), HDL (b), triglycerides (c), and total cholesterol (d) were performed using serum taken at week 0, 4 and 8 of DBR or control treatments. * High fat diet vs. high fat diet + DBR is statistically significant difference (p < 0.05). ^ Low fat diet vs. high fat diet is statistically significant. ∨ Low fat diet vs. high fat diet + DBR is statistically significant