Fig. 5
From: Activation of myeloid dendritic cells, effector cells and regulatory T cells in lichen planus
Polyfunctional CD4+ T cells are induced upon TLR activation in patients with LP. PBMCs obtained from patients with LP (n = 10, black bars) and HCs (n = 19, white bars) were left unstimulated or were stimulated with the following TLR agonists: LPS/TLR4, CL097/TLR7-8, CpG/TLR9 and SEB. The cells were incubated with the agonists for 16 h and assessed using flow cytometry. Cytokine production (TNF, IL-22, IL-17, IL-10 and IFN-γ) from stimulated CD3+CD4+ T cells was subtracted from the baseline levels. The results are shown as the mean ± SEM. *P < 0.05, **P < 0.01 when compared with the HC group