Fig. 1
From: Activation of myeloid dendritic cells, effector cells and regulatory T cells in lichen planus
TLR activation increased the frequency of TNF-α+ mDC populations in patients with LP. PMBCs from patients with LP (n = 13, closed circles) and HC (n = 19, open circles) were left unstimulated or were stimulated with the following TLR agonists: LPS/TLR4, imiquimod/TLR7, CL097/TLR7-8, CpG/TLR9 and SEB. The cells were incubated with the agonists for 16 h and assessed using flow cytometry. a Production of TNF-α in mDCs (CD11c+HLA-DR+TNF-α+). b IFN-α secretion by pDCs (CD123+HLA-DR+IFN-α+) was subtracted from unstimulated levels. The results are shown as the mean ± SEM. *P < 0.01 when compared with the HC group