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Table 2 Proteins with altered expression in airway disease

From: Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway inflammation

Acc. Protein Asthma + CRS vs control Asthma only vs control Asthma + CRS vs Asthma only
A B A B A B
Aa
 Q8TAX7 MUC7 +4.0 +1.4 +2.9 +1.8   
 P68871 HBB +2.2 +1.3 +2.0 +2.7   
 P00738 HP +1.8 +1.3 +1.7 +1.8   
 P02788 LTF −1.5 −1.3 −1.9 −1.6   
 Q9GZZ8 LACRT −1.3 −2.0 −1.5 −2.8   
Bb
 P02768 ALB +1.3 +1.4     
 P01857 IGHG1 +1.3 +1.6     
 P05109 S100A8 −1.5 −1.5     
 P06702 S100A9 −1.5 −1.4     
 P80511 S100A12 −1.4 −2.3     
Cc
 Q9HC84 MUC5B    +2.2 +2.4   
 P20930 FLG    −1.4 −2.9   
 P01591 IGJ    −1.3 −1.5   
 P01876 IGHA1    −1.4 −1.3   
 P01833 PIGR    −1.3 −1.4   
 Q86YZ3 HRNR    −1.8 −3.8   
Dd
 Q08380 LGALS3BP      +1.6 +1.5
 Q86YZ3 HRNR      +3.6 +1.3
 P05109 S100A8      −1.3 −2.1
 P06702 S100A9      −1.3 −1.9
 P80511 S100A12      −1.6 −1.8
 P60709 ACTB      −1.2 −1.5
 P35579 MYH9      −1.6 −1.6
 P08311 CTSG      −2.9 −1.5
  1. Only proteins with greater than 1.3-fold change in both pool A and pool B are presented. A negative value (“−”) means negative fold change of the first disease compared to second state, while a positive value (“+”) means positive fold change
  2. Acc GenBank accession number; ACTB actin, cytoplasmic 1; ALB serum albumin; CTSG cathepsin G; FLG filaggrin; HBB hemoglobin subunit B; HP haptoglobin; HRNR hornerin; IGHA1 Ig alpha-1 chain C region; IGHG1 Ig gamma-1 chain C region; IGJ Immunoglobulin J chain; LACRT extracellular glycoprotein lacritin; LGALS3BP Galectin-3-binding protein; LTF lactotransferrin; MUC5B mucin-5B; MUC7 mucin-7; MYH9 myosin-9; PIGR polymeric immunoglobulin receptor
  3. aProteins altered in both asthma + CRS and asthma only against the control
  4. bProteins altered in asthma + CRS compared to control
  5. cProteins altered in asthma only compared to control
  6. dProteins altered in asthma + CRS compared to asthma only