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Table 5 PD-L1 expression according to the stromal types in triple negative breast cancer

From: Expression of PD-L1 in triple-negative breast cancer based on different immunohistochemical antibodies

Parameters

Total

N = 218 (%)

Stromal type

p value

Desmoplastic

n = 138 (%)

Inflammatory

n = 63 (%)

Sclerotic

n = 17 (%)

PD-L1 (28-8) (T)

    

0.005

 Negative

191 (87.6)

127 (92.0)

48 (76.2)

16 (94.1)

 

 Positive

27 (12.4)

11 (8.0)

15 (23.8)

1 (5.9)

 

PD-L1 (E1L3N) (T)

    

<0.001

 Negative

186 (85.3)

126 (91.3)

44 (69.8)

16 (94.1)

 

 Positive

32 (14.7)

12 (8.7)

19 (30.2)

1 (5.9)

 

PD-L1 (SP142) (T)

    

0.001

 Negative

194 (89.0)

130 (94.2)

48 (76.2)

16 (94.1)

 

 Positive

24 (11.0)

8 (5.8)

15 (23.8)

1 (5.9)

 

PD-L1 (28-8) (I)

    

<0.001

 Negative

138 (63.3)

100 (72.5)

25 (39.7)

13 (76.5)

 

 Positive

80 (36.7)

38 (27.5)

38 (60.3)

4 (23.5)

 

PD-L1 (E1L3N) (I)

    

<0.001

 Negative

136 (62.4)

103 (74.6)

20 (31.7)

13 (76.5)

 

 Positive

82 (37.6)

35 (25.4)

43 (68.3)

4 (23.5)

 

PD-L1 (SP142) (I)

    

<0.001

 Negative

176 (80.7)

121 (87.7)

40 (63.5)

15 (88.2)

 

 Positive

42 (19.3)

17 (12.3)

23 (36.5)

2 (11.8)

 
  1. T tumor cell, I immune cell