From: Resveratrol increases AdipoR1 and AdipoR2 expression in type 2 diabetic nephropathy
Db/m control | Db/m Res | Db/db control | Db/db Res | |
---|---|---|---|---|
Body weight (g) | 30.6 ± 1.6 | 29.7 ± 2.0 | 40.3 ± 5.3* | 41.8 ± 4.3* |
Kidney weight (g) | 0.19 ± 0.01 | 0.19 ± 0.03 | 0.21 ± 0.03 | 0.22 ± 0.02 |
FBS (mg/dL) | 169 ± 53 | 180 ± 35 | 242 ± 49* | 247 ± 91* |
HbA1c (%) | 4.1 ± 0.1 | 4.1 ± 0.1 | 12.2 ± 1.8* | 12.7 ± 1.0* |
BUN (mg/dL) | 0.32 ± 0.05 | 0.35 ± 0.04 | 0.36 ± 0.03 | 0.37 ± 0.02 |
Serum Cr (mg/dL) | 0.079 ± 0.008 | 0.081 ± 0.010 | 0.082 ± 0.011 | 0.080 ± 0.009 |
Serum adiponectin (μg/mL) | 11.6 ± 1.0 | 11.8 ± 0.9 | 4.5 ± 0.4* | 6.4 ± 0.5** |
Urine volume (mL) | 0.7 ± 0.2 | 0.8 ± 0.2 | 8.7 ± 2.2* | 3.3 ± 1.1 |
24-h albuminuria (μg/day) | 10.0 ± 4.2 | 9.0 ± 1.4 | 140.0 ± 34.2* | 30.1 ± 15.5 |