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Table 5 Classification performance of the chosen parameters for the score sheet (by experts)

From: Development and validation of a classification and scoring system for the diagnosis of oral squamous cell carcinomas through confocal laser endomicroscopy

Parameters
(score sheet)
Occurrence frequency,  %; anomalies in Chi square test
(n = 95)
Correlations (n = 95)
Physiological mucosa
(n = 45)
OSCC
(n = 50)
P value P value
(2 tailed)
Spearman’s rho
Homogeneity 15.6 (7/45) 100 (50/50) <0.001 <0.001 0.936
Intercellular gaps 37.8 (17/45) 100 (50/50) <0.001 <0.001 0.880
Cell morphology 28.9 (13/45) 100 (50/50) <0.001 <0.001 0.949
Fluorescein leakage 22.2 (10/45) 78 (39/50) <0.001 <0.001 0.557
Vessel morphology 17.8 (8/45) 92 (46/50) <0.001 <0.001 0.748
  1. Occurrence frequency of anomalies (mildly or highly dysplastic) in physiological mucosa and OSCCs, Chi square test and Spearman’s correlation