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Table 4 Expression of serine/glycine metabolism-related proteins according to the histologic subtype of follicular carcinoma

From: Expression of serine/glycine metabolism-related proteins is different according to the thyroid cancer subtype

Parameters Total n = 112 (%) FC, minimally invasive type n = 99 (%) FC, widely invasive type n = 13 (%) p value
PHGDH in tumor 0.454
 Negative 58 (51.8) 50 (50.5) 8 (61.5)  
 Positive 54 (48.2) 49 (49.5) 5 (38.5)  
PSAT1 in tumor 1.000
 Negative 103 (92.0) 91 (91.9) 12 (92.3)  
 Positive 9 (8.0) 8 (8.1) 1 (7.7)  
PSPH in tumor 0.357
 Negative 101 (90.2) 88 (88.9) 13 (100.0)  
 Positive 11 (9.8) 11 (11.1) 0 (0.0)  
SHMT1 in tumor 0.689
 Negative 94 (83.9) 82 (82.8) 12 (92.3)  
 Positive 18 (16.1) 17 (17.2) 1 (7.7)  
GLDC in tumor 1.000
 Negative 96 (85.7) 85 (85.9) 11 (84.6)  
 Positive 16 (14.3) 14 (14.1) 2 (15.4)  
  1. PHGDH phosphoglycerate dehydrogenase; PSAT phosphoserine aminotransferase; PSPH phosphoserine phosphatase; SHMT serine hydromethyl transferase; GLDC glycine decarboxylase