Skip to main content

Table 1 Body weight, blood pressure and metabolic parameters 8 weeks after RDN

From: Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE-deficient rats

 

SD-sham n = 5

SD-RDN n = 6

ApoE−/−-sham n = 5

ApoE−/−-RDN n = 6

Body weight (g)

456.2 ± 25.64

474.14 ± 11.26

446.75 ± 3.68

456.2 ± 10

Heart weigth (g)

1.41 ± 0.04

1.45 ± 0.05

1.51 ± 0.06

1.45 ± 0.04

Heart rate (bpm)

360 ± 9

370 ± 10

341 ± 13

359 ± 7

Blood pressure (mmHg)

 Systolic

144 ± 5

137 ± 4

148 ± 12

136 ± 7

 Diastolic

116 ± 4

109 ± 10

121 ± 11

99 ± 8

 Stroke volume (µl)

210 ± 10

219 ± 5

203 ± 10

224 ± 9

 Ejection fraction (%)

61 ± 3

61 ± 1

59 ± 2

60 ± 2

 LVEDV (µl)

342 ± 11

357 ± 11

344 ± 8

372 ± 13

 LVESV (µl)

131 ± 12

137 ± 8

140 ± 11

148 ± 10

Serum chemistry

 GPT (U/l)

79.64 ± 7.53

70.5 ± 5.91*

109.66 ± 14.96

104.43 ± 10.26

 GOT (U/l)

178.36 ± 24.74

169.64 ± 13.83

222.22 ± 33.31

217.28 ± 32.1

 Creatinine (mg/dl)

0.306 ± 0.02

0.33 ± 0.01

0.33 ± 0.02

0.29 ± 0.03

 Glucose (mg/dl)

235.2 ± 8.24

268.71 ± 17.18

328.25 ± 28.51

289.33 ± 25.65

 Cholesterol (mg/dl)

48.2 ± 3.28§

45.71 ± 3.21#

131.5 ± 17.54

152.5 ± 13.63

 Triglycerides (mg/dl)

30.6 ± 7.04§

30.57 ± 8.05#

152.2 ± 27.41

152.5 ± 18.44

 LDL (mg/dl)

10.96 ± 1.15§

10.5 ± 0.94#

52.3 ± 6.62

65.28 ± 9.61

 HDL (mg/dl)

37.58 ± 1.36§

34.93 ± 3.36#

11.7 ± 1.67

15.78 ± 1.81

  1. Values are mean ± SEM
  2. LVEDV left ventricular end-diastolic volume, LVESV left ventricular end-systolic volume, GPT glutamat-pyruvat-transaminase, GOT glutamat-oxalacetat-transaminase, HDL high-density lipoprotein, LDL low-density lipoprotein
  3. * p < 0.05 SD-RDN vs. ApoE−\−-RDN
  4. §p < 0.01 SD-sham vs. ApoE−\−-sham
  5. #p < 0.01 SD-RDN vs. ApoE−\−-RDN (one-way-Anova followed by Tukey´s multiple comparisons test)