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Table 1 Body weight, blood pressure and metabolic parameters 8 weeks after RDN

From: Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE-deficient rats

  SD-sham n = 5 SD-RDN n = 6 ApoE−/−-sham n = 5 ApoE−/−-RDN n = 6
Body weight (g) 456.2 ± 25.64 474.14 ± 11.26 446.75 ± 3.68 456.2 ± 10
Heart weigth (g) 1.41 ± 0.04 1.45 ± 0.05 1.51 ± 0.06 1.45 ± 0.04
Heart rate (bpm) 360 ± 9 370 ± 10 341 ± 13 359 ± 7
Blood pressure (mmHg)
 Systolic 144 ± 5 137 ± 4 148 ± 12 136 ± 7
 Diastolic 116 ± 4 109 ± 10 121 ± 11 99 ± 8
 Stroke volume (µl) 210 ± 10 219 ± 5 203 ± 10 224 ± 9
 Ejection fraction (%) 61 ± 3 61 ± 1 59 ± 2 60 ± 2
 LVEDV (µl) 342 ± 11 357 ± 11 344 ± 8 372 ± 13
 LVESV (µl) 131 ± 12 137 ± 8 140 ± 11 148 ± 10
Serum chemistry
 GPT (U/l) 79.64 ± 7.53 70.5 ± 5.91* 109.66 ± 14.96 104.43 ± 10.26
 GOT (U/l) 178.36 ± 24.74 169.64 ± 13.83 222.22 ± 33.31 217.28 ± 32.1
 Creatinine (mg/dl) 0.306 ± 0.02 0.33 ± 0.01 0.33 ± 0.02 0.29 ± 0.03
 Glucose (mg/dl) 235.2 ± 8.24 268.71 ± 17.18 328.25 ± 28.51 289.33 ± 25.65
 Cholesterol (mg/dl) 48.2 ± 3.28§ 45.71 ± 3.21# 131.5 ± 17.54 152.5 ± 13.63
 Triglycerides (mg/dl) 30.6 ± 7.04§ 30.57 ± 8.05# 152.2 ± 27.41 152.5 ± 18.44
 LDL (mg/dl) 10.96 ± 1.15§ 10.5 ± 0.94# 52.3 ± 6.62 65.28 ± 9.61
 HDL (mg/dl) 37.58 ± 1.36§ 34.93 ± 3.36# 11.7 ± 1.67 15.78 ± 1.81
  1. Values are mean ± SEM
  2. LVEDV left ventricular end-diastolic volume, LVESV left ventricular end-systolic volume, GPT glutamat-pyruvat-transaminase, GOT glutamat-oxalacetat-transaminase, HDL high-density lipoprotein, LDL low-density lipoprotein
  3. * p < 0.05 SD-RDN vs. ApoE−\−-RDN
  4. §p < 0.01 SD-sham vs. ApoE−\−-sham
  5. #p < 0.01 SD-RDN vs. ApoE−\−-RDN (one-way-Anova followed by Tukey´s multiple comparisons test)