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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Longitudinal study of DNA methylation during the first 5 years of life

Fig. 2

Genomic characterization of the dmCpGs with time. a Stacked bar chart describing the proportion of CpG sites in the selected subsets of interest according to their CpG Island status and relative to the background Illumina® 450 k (All) proportions. Hypermethylated probes are enriched in CpG island shores while hypomethylated CpG sites are enriched in non CpG islands (CGIs) (Pearson’s Chi squared test; p < 0.001, OR = 1.60 and p < 0.001, OR = 1.91, respectively). b Stacked bar chart showing the proportion of selected CpG sites with respect to their genomic location and relative to the background (All). Hypermethylated CpG sites are enriched mainly in exons (Pearson’s Chi squared test; p < 0.001, OR = 1.37), and hypomethylated probes in introns (Pearson’s Chi squared test; p < 0.001, OR = 1.41)

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