Fig. 8

Levels of circulating IL-6 are increased in arthritic ApoE^−/− mice. Serum levels of IL-6 from non-arthritic and arthritic C57BL/6 (control, n = 2 non-arthritic and n = 13 arthritic) and ApoE^−/− (n = 3 non-arthritic and n = 6 arthritic) mice at 4–6 months. Data are represented as mean ± SEM. Asterisk denotes statistically significant differences. *p < 0.05, ***p < 0.001