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Table 1 Demographical and clinical characteristics of the SLE patients (n = 72)

From: Anti-dsDNA antibodies bind to TLR4 and activate NLRP3 inflammasome in lupus monocytes/macrophages

Age (years)

30.2 ± 12.6

Sex (male/female)

7/65

Newly-onset (no.)

27

Kidney involvement (no.)

42

ESR (mm/h)

39.1 ± 24.8

CRP (mg/L)

7.7 ± 12.3

Anti-dsDNA Abs (IU/ml)a

2.7 ± 1.6

ANA (IU/ml)b

7.4 ± 3.2

C3 (g/L)

0.5 ± 0.3

C4 (g/L)

0.1 ± 0.06

SLEDAI

9.2 ± 5.9

  1. The healthy control group consisted 4 men and 32 women with a mean ± SD, age of 28 ± 10.7 years
  2. SLE systemic lupus erythematosus, Anti-dsDNA anti-double stranded DNA antibodies, SLEDAI systemic lupus erythematosus disease activity index
  3. a,bConcentration of 0–0.9 IU/ml was recognized as negative in this assay