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Table 1 Demographical and clinical characteristics of the SLE patients (n = 72)

From: Anti-dsDNA antibodies bind to TLR4 and activate NLRP3 inflammasome in lupus monocytes/macrophages

Age (years) 30.2 ± 12.6
Sex (male/female) 7/65
Newly-onset (no.) 27
Kidney involvement (no.) 42
ESR (mm/h) 39.1 ± 24.8
CRP (mg/L) 7.7 ± 12.3
Anti-dsDNA Abs (IU/ml)a 2.7 ± 1.6
ANA (IU/ml)b 7.4 ± 3.2
C3 (g/L) 0.5 ± 0.3
C4 (g/L) 0.1 ± 0.06
SLEDAI 9.2 ± 5.9
  1. The healthy control group consisted 4 men and 32 women with a mean ± SD, age of 28 ± 10.7 years
  2. SLE systemic lupus erythematosus, Anti-dsDNA anti-double stranded DNA antibodies, SLEDAI systemic lupus erythematosus disease activity index
  3. a,bConcentration of 0–0.9 IU/ml was recognized as negative in this assay