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Table 3 Modulation of adjuvant arthritis development in rats by administration of ultrafiltrates obtained from PBMCs of RA patients

From: Vaccination with endosomal unknown epitopes produces therapeutic response in rheumatoid arthritis patients and modulates adjuvant arthritis of rats

Days from AI

UF-S**

UF-f/t**

UF-R

Rifamycin

Saline sol.

AA score

Median

AA score

Median

AA score

Median

AA score

Median

AA score

Median

11

00000

00233

0

00000

11246

0.5

00122

22223

2

00001

11222

1

00011

22245

1.5

15

00012

24457

2

02222

33357

2.5

12223

33344

3

02333

33444

3

24445

55666

3

19

11244

45588

4

02344

45557

4

24555

66788

5.5

25555

66788

5.5

46666

67777

5.5

23

13333

55788

4

03344

55567

4.5

24555

66888

5.5

33344

56668

4.5

45555

66678

4.5

27

12223

36778

3

02344

44457

4

23455

55888

5

33334

55668

4.5

44445

55668

4.5

  1. Ten rats per group were injected with 0.5 µg/mL of each ultrafiltrate or 0.5 mL of Rifamycin SV (250 µmL) or saline solution at 7 and 8 days after arthritis induction
  2. AA adjuvant arthritis, AI arthritis induction, RA rheumatoid arthritis
  3. ** p < 0.05 vs saline solution