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Table 3 Modulation of adjuvant arthritis development in rats by administration of ultrafiltrates obtained from PBMCs of RA patients

From: Vaccination with endosomal unknown epitopes produces therapeutic response in rheumatoid arthritis patients and modulates adjuvant arthritis of rats

Days from AI UF-S** UF-f/t** UF-R Rifamycin Saline sol.
AA score Median AA score Median AA score Median AA score Median AA score Median
11 00000
00233
0 00000
11246
0.5 00122
22223
2 00001
11222
1 00011
22245
1.5
15 00012
24457
2 02222
33357
2.5 12223
33344
3 02333
33444
3 24445
55666
3
19 11244
45588
4 02344
45557
4 24555
66788
5.5 25555
66788
5.5 46666
67777
5.5
23 13333
55788
4 03344
55567
4.5 24555
66888
5.5 33344
56668
4.5 45555
66678
4.5
27 12223
36778
3 02344
44457
4 23455
55888
5 33334
55668
4.5 44445
55668
4.5
  1. Ten rats per group were injected with 0.5 µg/mL of each ultrafiltrate or 0.5 mL of Rifamycin SV (250 µmL) or saline solution at 7 and 8 days after arthritis induction
  2. AA adjuvant arthritis, AI arthritis induction, RA rheumatoid arthritis
  3. ** p < 0.05 vs saline solution