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Table 2 The effects of autologous ultrafiltrate on CD69 and CTLA-4 expression by PBMCs stimulated with CD3/CD28

From: Vaccination with endosomal unknown epitopes produces therapeutic response in rheumatoid arthritis patients and modulates adjuvant arthritis of rats

Donor

% CD69+/CD4+

% CD69+/CD4+CD25+

% CTLA-4+/CD4+

% CTLA-4+/CD4+CD25+

Normal (n = 1)

−25

−18

+4

−33

Patients (n = 3)

−7

−15

+4

+3

  1. The results are shown as the untreated cells minus cells plus lysate. CD69 and CTLA-4 were down-regulated in the normal donor