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Table 2 The effects of autologous ultrafiltrate on CD69 and CTLA-4 expression by PBMCs stimulated with CD3/CD28

From: Vaccination with endosomal unknown epitopes produces therapeutic response in rheumatoid arthritis patients and modulates adjuvant arthritis of rats

Donor % CD69+/CD4+ % CD69+/CD4+CD25+ % CTLA-4+/CD4+ % CTLA-4+/CD4+CD25+
Normal (n = 1) −25 −18 +4 −33
Patients (n = 3) −7 −15 +4 +3
  1. The results are shown as the untreated cells minus cells plus lysate. CD69 and CTLA-4 were down-regulated in the normal donor