Vaccination with endosomal unknown epitopes produces therapeutic response in rheumatoid arthritis patients and modulates adjuvant arthritis of rats

Table 1 Disease activity score after subcutaneous injection of autologous ultrafiltrates in early rheumatoid patients

Ultrafiltrates^a	Pts	ACR ≥ 20^b (10th day) vs (30th day)		RR°	95 %	CI	p value
Ultrafiltrates^a	Pts	(%pts10th day)	(%pts 30th day)	RR°	95 %	CI	p value
UF-R rifamycin SV (from 5 × 10⁶ cells/mL)	46	17 (37)	19 (41)	0.90	0.54	1.49	NS
Ul-f/t freeze/taw (from 5 × 10⁶ cells/mL)	58	19 (33)	22 (38)	0.86	0.53	1.42	NS
UF-sf (from acellular sin. fluid)	11	7 (64)	7 (64)	1	0.53	1.88	–

^aOne subcutaneous administration in two consecutive days. For doses, see text
^bAmerican College Rheumatology criteria ≥20° relative risks (RR), calculated using Chi square Pearson test

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