From: Proteomic analysis of short-term preload-induced eccentric cardiac hypertrophy
Protein | Spot number | Average sham | Average shunt | T test | Regulation (%) |
---|---|---|---|---|---|
Cytoskeletal and contractile proteins | |||||
 Actin, aortic smooth muscle | 5 | 0266 | 0126 | 0007 | −53 |
 Actin, cytoplasmic 1 | 22 | 0085 | 0188 | 0030 | 121 |
 Myosin-6 | 20 | 0010 | 0026 | 0029 | 167 |
 Myosin regulatory light chain 2, ventricular/cardiac muscle isoform | 14 | 0743 | 0347 | 0021 | −53 |
 Tropomyosin alpha-1 chain | 21 | 0037 | 0097 | 0030 | 162 |
 Tubulin beta-2C chain | 4 | 0010 | 0026 | 0006 | 166 |
Metabolism | |||||
 β-enolase | 3 | 0052 | 0187 | 0005 | 263 |
 β-enolase | 34 | 0057 | 0211 | 0047 | 271 |
 Delta-aminolevulinic acid dehydratase | 25 | 0018 | 0121 | 0037 | 571 |
 L-lactate dehydrogenase B chain | 13 | 0059 | 0028 | 0018 | −52 |
Mitochondrial proteins | |||||
 ATP synthase subunit alpha, mitochondrial (Complex V) | 30 | 0297 | 0618 | 0041 | 108 |
 ATP synthase subunit d, mitochondrial (Complex V) | 31 | 0266 | 0068 | 0042 | −74 |
 ATP synthase subunit alpha, mitochondrial (Complex V) | 33 | 0045 | 0099 | 0047 | 119 |
 ATP synthase subunit beta (Complex V) | 12 | 0069 | 0147 | 0023 | 115 |
 ATP synthase subunit beta, mitochondrial (Complex V) | 38 | 0044 | 0086 | 0018 | 96 |
 Cytochrome b-c1 complex subunit 1 (Complex III) | 7 | 0089 | 0027 | 0012 | −69 |
 Cytochrome b-c1 complex subunit 1, mitochondrial (Complex III) | 32 | 0005 | 0025 | 0043 | 368 |
 Electron transfer flavoprotein subunit beta | 8 | 0094 | 0249 | 0015 | 164 |
 60 kDa heat shock protein, mitochondrial | 24 | 0041 | 0081 | 0034 | 97 |
 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | 16 | 0146 | 0071 | 0025 | −51 |
 Thioredoxin-dependent peroxide reductase, mitochondrial | 35 | 0016 | 0004 | 0048 | −74 |
Others | |||||
 α-1-antitrypsin 1-2 | 1 | 0813 | 0345 | 0002 | −58 |
 COP9 signalosome complex subunit 4 | 18 | 0049 | 0113 | 0026 | 132 |
 Heat shock cognate 71 kDa protein | 11 | 0061 | 0013 | 0039 | −79 |
 Polymerase I and transcript release factor | 28 | 0304 | 0657 | 0039 | 116 |