Table 2 Gene description and regression coefficients from Cox regression analysis
From: An 18 gene expression-based score classifier predicts the clinical outcome in stage 4 neuroblastoma
Symbol | Gene name | Chromosomea | Function | Coefficient |
|---|---|---|---|---|
ADCY1 | Adenylate cyclase 1 (brain) | 7p12.3 | Drug-target, membrane, signal transduction | −0.963 |
AKR1C1 | Aldo–keto reductase family 1, member C1 | 10p15.1 | Drug-target | −0.740b and −0.681 |
ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 1p36.13 | Signal transduction | −2.902 |
BTBD3 | BTB (POZ) domain containing 3 | 20p12.2 | – | 0.807 |
C9orf130 | Chromosome 9 open reading frame 130 | 9q22.32 | – | 0.612 |
FOXP1 | Forkhead box P1 | 3p14.1 | TF, transcription regulator activity | −0.984 |
GFRA3 | GDNF family receptor alpha 3 | 5q31.2 | Development, differentiation, membrane, signal transduction | −0.916 |
GNAI1 | Guanine nucleotide binding protein | 7q21.11 | Membrane, signal transduction | −1.049b and −1.48 |
HOXC6 | Homeobox C6 | 12q13.3 | TF, development, transcription regulator activity, transcriptional repressor activity | −0.786 |
ING3 | Inhibitor of growth family, member 3 | 7q31.31 | – | −0.918 |
LOC153682 | Uncharacterized LOC153682 | 5p13.1 | – | −0.886 |
PGM2L1 | Phosphoglucomutase 2-like 1 | 11q13.4 | – | −1.075 |
RUNDC3B | RUN domain containing 3B | 7q21.12 | – | −1.0156 |
PRKACB | Protein kinase, cAMP-dependent, catalytic, beta | 1p31.1 | Kinase, signal transduction | −1.071 |
PTPRH | Protein tyrosine phosphatase, receptor type, H | 19q13.42 | Membrane | −1.644 |
SCN3A | Sodium channel, voltage-gated, type III, alpha subunit | 2q24.3 | Drug-target, membrane | −0.443 |
SNAP91 | Synaptosomal-associated protein, 91 K-Da homologue (mouse) | 6q14.2 | Membrane | −0.969 |
SOX4 | SRY (sex determining region Y)-box 4 | 6p22.3 | TF, development, transcription regulator activity | −1.651 |