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Table 2 Gene description and regression coefficients from Cox regression analysis

From: An 18 gene expression-based score classifier predicts the clinical outcome in stage 4 neuroblastoma

Symbol Gene name Chromosomea Function Coefficient
ADCY1 Adenylate cyclase 1 (brain) 7p12.3 Drug-target, membrane, signal transduction −0.963
AKR1C1 Aldo–keto reductase family 1, member C1 10p15.1 Drug-target −0.740b and −0.681
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 1p36.13 Signal transduction −2.902
BTBD3 BTB (POZ) domain containing 3 20p12.2 0.807
C9orf130 Chromosome 9 open reading frame 130 9q22.32 0.612
FOXP1 Forkhead box P1 3p14.1 TF, transcription regulator activity −0.984
GFRA3 GDNF family receptor alpha 3 5q31.2 Development, differentiation, membrane, signal transduction −0.916
GNAI1 Guanine nucleotide binding protein 7q21.11 Membrane, signal transduction −1.049b and −1.48
HOXC6 Homeobox C6 12q13.3 TF, development, transcription regulator activity, transcriptional repressor activity −0.786
ING3 Inhibitor of growth family, member 3 7q31.31 −0.918
LOC153682 Uncharacterized LOC153682 5p13.1 −0.886
PGM2L1 Phosphoglucomutase 2-like 1 11q13.4 −1.075
RUNDC3B RUN domain containing 3B 7q21.12 −1.0156
PRKACB Protein kinase, cAMP-dependent, catalytic, beta 1p31.1 Kinase, signal transduction −1.071
PTPRH Protein tyrosine phosphatase, receptor type, H 19q13.42 Membrane −1.644
SCN3A Sodium channel, voltage-gated, type III, alpha subunit 2q24.3 Drug-target, membrane −0.443
SNAP91 Synaptosomal-associated protein, 91 K-Da homologue (mouse) 6q14.2 Membrane −0.969
SOX4 SRY (sex determining region Y)-box 4 6p22.3 TF, development, transcription regulator activity −1.651
  1. Coefficients calculated in the training set
  2. TF transcriptional factor
  3. aEnsembl cytogenetic band
  4. bCoefficients of two separate probes for the same gene