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Table 1 Clinical features of stage 4 NB patients

From: An 18 gene expression-based score classifier predicts the clinical outcome in stage 4 neuroblastoma

Variables Seeger cohorta Versteeg cohortb Validation cohort 1c Validation cohort 2d
n = 102 n = 40 n = 214 n = 27
Sex
 Male N/A 24 (60 %) 122 (60.1) 13 (48.1)
 Female N/A 16 (40 %) 81 (39.9) 14 (51.8)
 N/A    12  
Age
 Median (years)   2.5 2.7 2.6
 <18 months N/A 8 (20.0 %) 68 (31.8 %) 8 (29.6)
 ≥18 months N/A 32 (30.0 %) 146 (68.2 %) 19 (70.4)
MYCN amplification
 Yes 0 (0 %) 15 (37.5 %) 68 (31.9 %) 14 (51.8)
 No 102 (100 %) 25 (62.5 %) 145 (68.1 %) 13 (48.1)
  1. N/A not available, NB neuroblastoma
  2. a,b,cMicroarray gene expression data downloaded from GEO datasets (GSE16254, GSE16476, GSE45547)
  3. dMicroarray gene expression data produced from a new cohort of stage 4 tumors (GSE79910)