Single dose GLP toxicity and biodistribution study of a conditionally replicative adenovirus vector, CRAd-S-pk7, administered by intracerebral injection to Syrian hamsters

Table 2 Survival of animals treated with CRAd-S-pk7 viral vector after intracranial injection

Days post treatment	Vehicle	1 × 10⁷ VP	1 × 10⁸ VP	1 × 10⁹ VP	Survival (%)
Day 6	10/10	10/10	10/10	10/10	100
Day 34	10/10	10/10	10/10	10/10	100
Day 62	10/10	10/10	10/10	10/10	100

Regardless of titer of vector treatment, all animals made it to their predetermined time points (days 6, 34, and 62) without any observable toxicity
VP viral particles

ISSN: 1479-5876