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Table 3 MSC production between 2007 and 2015

From: Clinical-scale expansion of mesenchymal stromal cells: a large banking experience

Criteria

Min.

Max.

Median

MSC culture parameters

 Donor age (years)

18

52

26.7

 BM sample volume (mL)

25

70

50

 Mononuclear cells post-Ficoll (×106)

124

956

280

 CFU-F (number per 2 × 106 cells)

2

96

25

 Final MSC yields (×106)

19

5431

546

 PDL (P1-harvest)

2.38

7.18

4.69

 DT in hours (P1-harvest)

46.8

141

71.7

 Viability (%)

72

100

85

 Number of aliquots (=bags)/culture

1

45

4

 Number of cells/aliquot (×106)

19

189

110