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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: MiR-19a, miR-122 and miR-223 are differentially regulated by hepatitis B virus X protein and involve in cell proliferation in hepatoma cells

Fig. 8

The role of PTEN, cyclin G1, and c-myc in HBx-mediated growth of HepG2 cells. The proliferation ability of HepG2-pcDNA3.1-HBx was analyzed using the EdU incorporation assays a after transfection with pcDNA3.1-PTEN or co-transfection with pcDNA3.1-PTEN and miR-19a inhibitor; b after transfection with cyclin G1 siRNA (si-cyclin G1) or co-transfection with pcDNA3.1-cyclin G1 and miR-223 mimics; c after transfection with c-myc siRNA (si-c-myc) or co-transfection with pcDNA3.1-c-myc and miR-122 mimics. Data represents the mean ± SEM, n = 3, *P < 0.05; **P < 0.01 (One-way ANOVA followed by Bonferroni test)

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