Skip to main content

Advertisement

Table 4 Correlation between PFN2 expression and clinicopathologic features in ESCC from Han and Kazakh population

From: PFN2, a novel marker of unfavorable prognosis, is a potential therapeutic target involved in esophageal squamous cell carcinoma

Variables PFN2 expression in Han ethnic PFN2 expression in Kazakh ethnic
Total cases Low n (%) High n (%) P value Total cases Low n (%) High n (%) P value
Gender     0.817     0.173
 Male 137 23 (16.8) 114 (83.2)   108 17 (15.7) 91 (84.3)  
 Female 55 10 (18.2) 45 (81.8)   60 5 (8.3) 55 (91.7)  
Age (years)     0.658     0.916
 <59 98 18 (18.4) 80 (81.6)   101 13 (12.9) 88 (87.1)  
 ≥59 94 15 (16.0) 79 (84.0)   67 9 (13.4) 58 (86.6)  
Differentiation     0.162     0.305
 Well 67 15 (22.4) 52 (77.6)   39 7 (17.9) 32 (82.1)  
 Moderate + poor 125 18 (14.4) 107 (85.6)   129 15 (11.6) 114 (88.4)  
Invasion depth     0.004*     0.393
 T1–T2 79 21 (26.6) 58 (73.4)   83 9 (10.8) 74 (89.2)  
 T3–T4 113 12 (10.6) 101 (89.4)   85 13 (15.3) 72 (84.7)  
Lymph node metastasis     0.945     0.010*
 No 127 22 (17.3) 105 (82.7)   79 16 (20.3) 63 (79.7)  
 Yes 65 11 (16.9) 54 (83.1)   89 6 (6.7) 83 (93.3)  
TNM stage     0.822     0.796
 I + II 154 26 (16.9) 128 (83.1)   111 14 (12.6) 97 (87.4)  
 III + IV 38 7 (18.4) 31 (81.6)   57 8 (14.0) 49 (86.0)  
  1. * P < 0.05, as determined by Pearson’s χ2 test