Table 4 Correlation between PFN2 expression and clinicopathologic features in ESCC from Han and Kazakh population
Variables | PFN2 expression in Han ethnic | PFN2 expression in Kazakh ethnic | ||||||
|---|---|---|---|---|---|---|---|---|
Total cases | Low n (%) | High n (%) | P value | Total cases | Low n (%) | High n (%) | P value | |
Gender | Â | Â | Â | 0.817 | Â | Â | Â | 0.173 |
 Male | 137 | 23 (16.8) | 114 (83.2) |  | 108 | 17 (15.7) | 91 (84.3) |  |
 Female | 55 | 10 (18.2) | 45 (81.8) |  | 60 | 5 (8.3) | 55 (91.7) |  |
Age (years) | Â | Â | Â | 0.658 | Â | Â | Â | 0.916 |
 <59 | 98 | 18 (18.4) | 80 (81.6) |  | 101 | 13 (12.9) | 88 (87.1) |  |
 ≥59 | 94 | 15 (16.0) | 79 (84.0) |  | 67 | 9 (13.4) | 58 (86.6) |  |
Differentiation | Â | Â | Â | 0.162 | Â | Â | Â | 0.305 |
 Well | 67 | 15 (22.4) | 52 (77.6) |  | 39 | 7 (17.9) | 32 (82.1) |  |
 Moderate + poor | 125 | 18 (14.4) | 107 (85.6) |  | 129 | 15 (11.6) | 114 (88.4) |  |
Invasion depth | Â | Â | Â | 0.004* | Â | Â | Â | 0.393 |
 T1–T2 | 79 | 21 (26.6) | 58 (73.4) |  | 83 | 9 (10.8) | 74 (89.2) |  |
 T3–T4 | 113 | 12 (10.6) | 101 (89.4) |  | 85 | 13 (15.3) | 72 (84.7) |  |
Lymph node metastasis | Â | Â | Â | 0.945 | Â | Â | Â | 0.010* |
 No | 127 | 22 (17.3) | 105 (82.7) |  | 79 | 16 (20.3) | 63 (79.7) |  |
 Yes | 65 | 11 (16.9) | 54 (83.1) |  | 89 | 6 (6.7) | 83 (93.3) |  |
TNM stage | Â | Â | Â | 0.822 | Â | Â | Â | 0.796 |
 I + II | 154 | 26 (16.9) | 128 (83.1) |  | 111 | 14 (12.6) | 97 (87.4) |  |
 III + IV | 38 | 7 (18.4) | 31 (81.6) |  | 57 | 8 (14.0) | 49 (86.0) |  |