Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples

Table 3 Cox’s regression analysis demonstrating the prognostic potential of mutations identified in this study

Variable	Hazard ratio	95 % CI	P
Age of onset (<50 years old)	0.262	0.062–1.102	0.068
Lymph node metastasis	4.559	1.582–13.139	0.005
Tumor grade	1.093	0.424–2.820	0.854
PIK3CA mutations	1.421	0.282–7.163	0.670
KRAS mutations	1.635	0.493–5.414	0.421
EGFR mutations	3.639	1.221–10.850	0.020

ISSN: 1479-5876