Skip to main content

Table 6 Single hormone degree centrality (DC) among CFS patients and healthy controls

From: Altered neuroendocrine control and association to clinical symptoms in adolescent chronic fatigue syndrome: a cross-sectional study

 

CFS patients

Healthy controls

Difference in DC (95 % CI, CFS patients—healthy controls)

p value*

Plasma norepinephrine

0.36

0.44

−0.09 (−0.15 to −0.03)

0.003

Urine norepinephrine:creatinine ratio

0.49

1.00

−0.51 (−0.57 to −0.44)

<0.001

Plasma epinephrine

0.59

0.17

0.42 (0.36–0.48)

<0.001

Urine epinephrine:creatinine ratio

0.72

0.38

0.34 (0.28–0.40)

<0.001

Plasma ACTH

0.54

0.55

−0.02 (−0.08 to 0.04)

0.572

Plasma cortisol

0.78

0.46

0.33 (0.26–0.39)

<0.001

Urine cortisol:creatinine ratio

1.00

0.63

0.37 (0.31–0.43)

<0.001

Plasma TSH

0.36

0.65

−0.29 (−0.35 to −0.24)

<0.001

Plasma FT4

0.67

0.63

0.04 (−0.02 to 0.10)

0.231

  1. Italic values indicate significance of p value (p < 0.05)
  2. CFS chronic fatigue syndrome, CI confidence interval, ACTH adrenocorticotrophic hormone, TSH thyroid stimulating hormone, FT4 free thyroxine
  3. * t test