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Table 2 Clinical characteristics of the study group, n = 51

From: Next-generation sequencing for diagnosis of thoracic aortic aneurysms and dissections: diagnostic yield, novel mutations and genotype phenotype correlations

Clinical characteristics of the study group
Age at the genetic inquest (mean ± SD, years) 44.8 ± 13.8
Male sex (n, %) 35 (68.6)
AAD (n,  %) 17 (33.3)
Age at AAD (mean ± SD, years) 40.1 ± 13.0
Planned TAA surgery (n, %) 25 (49)
Age at planned TAA surgery (mean ± SD, years) 42.2 ± 17
Planned TAA surgery—first procedure in the patient (n, %) 19 (37.3)
Age at the planned TAA surgery- first procedure in the patient (mean ± SD, years) 44 ± 16.8
TAA with no criteria for surgery (n, %) 15 (29.4)
Age at last examination (mean ± SD, years) 39.9 ± 14.9
Suspected MFS (n, %) 13 (25.5)
Familial TAAD 25 (49)
Associated structural abnormalities (n, %)
BAV 11 (21.6)
CoA + BAV 1 (1.9)
ASD and LVNC 1 (1.9)
Other CV diseases (n, %)
Stroke 3 (5.8)
CAD 6 (11.7)
Peripheral artery aneurysms 3 (5.8)
Hypertension 33 (64.7)
Other diseases (n, %)
Mild-to-moderate intellectual disability 2 (3.9)
Rheumatid arthritis 1 (1.9)