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Table 5 Incidence of hypertension by serum uric acid quartile in normal-eGFR subjects

From: Associations between serum uric acid and the incidence of hypertension: a Chinese senior dynamic cohort study

Model N (%) Hazard ratio 95 % CI P-value
Model A: unadjusted
 Quartile 1 844 (24.5 %) 0.000
 Quartile 2 872 (25.4 %) 1.738 1.321–2.287 0.000
 Quartile 3 855 (24.9 %) 2.166 1.666–2.815 0.000
 Quartile 4 867 (25.2 %) 3.065 2.386–3.937 0.000
 SUA as a continuous variable (μmol/L) 3438 2.061 1.758–2.416 0.000
Model B: model A adjusted for age and sex
 Quartile 1 0.000
 Quartile 2 1.761 1.331–2.329 0.000
 Quartile 3 2.305 1.751–3.035 0.000
 Quartile 4 3.320 2.535–4.347 0.000
 SUA as a continuous variable (μmol/L) 2.040 1.739–2.392 0.000
Model C: model B further adjusted for other confounders
 Quartile 1 0.000
 Quartile 2 1.662 1.261–2.190 0.000
 Quartile 3 2.028 1.552–2.649 0.000
 Quartile 4 2.747 2.115–3.566 0.000
 SUA as a continuous variable (μmol/L) 1.807 1.519–2.150 0.000
  1. Model C was further adjusted for BMI, TG, eGFR, blood urea nitrogen, serum creatinine, plasma total protein, globulin, alanine aminotransferase, and direct bilirubin
  2. Quartiles based on serum uric acid levels: 1, <4.66 mg/dl; 2, 4.66–5.53 mg/dl; 3, 5.53–6.46 mg/dl; 4, ≥6.46 mg/dl