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Table 1 Characteristics of subjects [mean ± SD or N (%)] during baseline and follow-up periodsa by status at follow-up (hypertensive, nonhypertensive)

From: Associations between serum uric acid and the incidence of hypertension: a Chinese senior dynamic cohort study

Characteristic

Hypertensive subjects (N = 744)

Nonhypertensive subjects

(N = 2847)

P-value hypertensive versus nonhypertensive

Baseline

Follow-up

Baseline

Follow-up

Baseline

Follow-up

Male (%)

570 (76.61 %)

1980 (69.55 %)

0.000

0.000

Female (%)

174 (23.39 %)

867 (30.45 %)

  

Age (years)

61.47 ± 11.66

63.82 ± 11.63

55.61 ± 13.41

56.64 ± 13.33

0.000

0.000

BMI (kg/m2)

24.85 ± 3.04

24.76 ± 2.92

24.06 ± 3.03

24.01 ± 3.00

0.000

0.000

Overweight (BMI = 24–27.9 kg/m2)

350 (47.0 %)

346 (46.5 %)

1115 (40.5 %)

1130 (39.7 %)

Obese (BMI ≥ 28 kg/m2)

105 (14.1 %)

96 (12.9 %)

268 (9.4 %)

253 (8.9 %)

TG (mg/dl)

148.85 ± 95.69

149.73 ± 82.40

131.13 ± 95.69

134.67 ± 93.05

0.000

0.000

TC (mg/dl)

188.27 ± 32.47

189.82 ± 30.54

186.34 ± 32.47

186.73 ± 30.54

0.165

0.023

HDL (mg/dl)

51.80 ± 15.46

51.03 ± 14.69

53.35 ± 15.46

53.35 ± 15.46

0.059

0.000

eGFR (ml/min/1.73 m2)

86.96 ± 17.03

86.62 ± 15.69

90.51 ± 18.15

91.31 ± 22.62

0.000

0.000

≥60 (ml/min/1.73 m2)

711 (95.6 %)

712 (95.7 %)

2727 (95.8 %)

2738 (96.2 %)

<60 (ml/min/1.73 m2)

33 (4.4 %)

32 (4.3 %)

120 (4.2 %)

109 (3.8 %)

SUA (mg/dl)

6.26 ± 1.38

5.65 ± 1.20

5.50 ± 1.33

5.47 ± 1.27

0.000

0.000

BUN (mg/dl)

15.41 ± 3.53

15.49 ± 2.97

14.54 ± 3.53

14.57 ± 3.36

0.000

0.000

SCR (mg/dl)

0.92 ± 0.21

0.91 ± 0.18

0.88 ± 0.18

0.88 ± 0.17

0.000

0.000

SBP (mmHg)

140

140

119.62 ± 10.97

119.60 ± 10.46

0.000

0.000

DBP (mmHg)

90

90

70.01 ± 8.83

69.59 ± 8.41

0.000

0.000

FBG (mg/dl)

92.44 ± 22.71

98.93 ± 21.26

92.08 ± 18.02

94.42 ± 16.58

0.682

0.000

TP (g/L)

75.28 ± 4.06

74.69 ± 3.51

82.38 ± 10.83

73.68 ± 3.68

0.000

0.000

GLB (g/L)

29.66 ± 3.36

29.56 ± 3.07

28.27 ± 3.42

28.15 ± 3.27

0.000

0.000

ALB (g/L)

45.62 ± 2.61

45.12 ± 2.14

45.67 ± 2.70

45.52 ± 2.51

0.641

0.000

ALT (IU/L)

28.63 ± 22.08

25.25 ± 12.29

23.26 ± 17.98

22.19 ± 11.90

0.000

0.000

TBIL (mg/dl)

0.82 ± 0.29

0.90 ± 0.29

0.82 ± 0.31

0.84 ± 0.29

0.265

0.000

DBIL mg/dl)

0.12 ± 0.07

0.17 ± 0.10

0.19 ± 0.11

0.20 ± 0.09

0.000

0.000

Hypertension incidence (2007–2011)

 2006 n/incidence (baseline/follow-up)

0/0.00 % (932/821)

    

 2007 n/incidence (baseline/follow-up)

155/9.15 % (1694/1567)

    

 2008 n/incidence (baseline/follow-up)

191/11.27 % (1695/1636)

    

 2009 n/incidence (baseline/follow-up)

157/8.92 % (1761/1683)

    

 2010 n/incidence (baseline/follow-up)

122/6.89 % (1770/1615)

    

 2011 n/incidence (baseline/follow-up)

119/5.73 % (2077/2077)

    
  1. BMI body mass index; TG plasma levels of triglycerides; TC total cholesterol; HDL high-density lipoprotein; eGFR estimated glomerular filtration rate; SUA serum uric acid; BUN blood urea nitrogen; SCR serum creatinine; SBP systolic blood pressure; DBP diastolic blood pressure; FBG fasting plasma glucose; TP plasma total protein; GLB globulin; ALB albumin; ALT alanine aminotransferase; TBIL total bilirubin; DBIL direct bilirubin
  2. aMeans during the follow-up period are specified observations starting from the time of the baseline visit through the last visit or incidence of hypertension