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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: ERK1/2, MEK1/2 and p38 downstream signalling molecules impaired in CD56dimCD16+ and CD56brightCD16dim/− natural killer cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients

Fig. 1

Measurement of the ERK1/2 in CD56dimCD16+ NK cells. For a representative individual, CD56dimCD16+ NK cells were identified according to the surface expression of CD56 and CD16 (a) which was extrapolated onto a histogram plot to identify median fluorescence intensity (MFI) of ERK1/2 in US, K562 and PMA/I stimulated cells (b). Compared to the NFC, phosphorylated ERK1/2 in CD56dimCD16+ NK cells from CFS/ME patients was significantly reduced (c, *p < 0.05). Data are presented as MFI with interquartile range

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