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Table 4 Association of MED score as categorized variable with outcomes by Cox-regression models

From: Predictive role of the Mediterranean diet on mortality in individuals at low cardiovascular risk: a 12-year follow-up population-based cohort study

 

Mediterranean diet score

All

Score 0–3

Score 4–5

Score 6–9

Number

768

685

205

Incident CV events

72

42

11

 

HR

HR; 95 % CI; p

HR; 95 % CI; p

Crude

1

0.65; 0.44–0.95; 0.03

0.57; 0.30–1.07; 0.08

Model 1

1

0.68; 0.46–0.99; 0.05

0.60; 0.32–1.14; 0.12

Model 2

1

0.67; 0.45–0.98; 0.04

0.58; 0.31–1.11; 0.10

Model 3

1

0.68; 0.46–1.00; 0.05

0.59; 0.31–1.12; 0.11

CV mortality

49

28

7

 

HR

HR; 95 % CI; p

HR; 95 % CI; p

Crude

1

0.63; 0.40–1.00; 0.05

0.52; 0.24–1.16; 0.11

Model 1

1

0.65; 0.41–1.03; 0.07

0.65; 0.30–1.45; 0.30

Model 2

1

0.68; 0.42–1.09; 0.11

0.69; 0.31–1.54; 0.37

Model 3

1

0.68; 0.42–1.09; 0.11

0.69; 0.31–1.54; 0.37

All-cause mortality

116

82

22

 

HR

HR; 95 % CI; p

HR; 95 % CI; p

Crude

1

0.78; 0.59–1.03; 0.08

0.70; 0.44–1.10; 0.12

Model 1

1

0.79; 0.59–1.05; 0.10

0.83; 0.52–1.31; 0.42

Model 2

1

0.79; 0.59–1.05; 0.11

0.84; 0.53–1.34; 0.47

Model 3

1

0.80; 0.60–1.06; 0.12

0.85; 0.54–1.35; 0.50

CV risk score <10

Number

406

379

112

Incident CV events

28

16

3

 

HR

HR; 95 % CI; p

HR; 95 % CI; p

Crude

1

0.61; 0.33–1.12; 0.11

0.38; 0.12–1.26; 0.11

Model 1

1

0.62; 0.34–1.15; 0.13

0.40; 0.12–1.31; 0.13

Model 2

1

0.62; 0.33–1.16; 0.14

0.41; 0.12–1.35; 0.14

Model 3

1

0.61; 0.33–1.14; 0.12

0.38; 0.11–1.27; 0.12

CV mortality

21

10

3

 

HR

HR; 95 % CI; p

HR; 95 % CI; p

Crude

1

0.50; 0.24–1.07; 0.07

0.51; 0.15–1.71; 0.28

Model 1

1

0.52; 0.24–1.11; 0.09

0.55; 0.16–1.86; 0.34

Model 2

1

0.45; 0.21–0.97; 0.04

0.60; 0.18–2.02; 0.41

Model 3

1

0.46; 0.21–1.01; 0.05

0.59; 0.17–2.01; 0.40

All-cause mortality

50

31

9

 

HR

HR; 95 % CI; p

HR; 95 % CI; p

Crude

1

0.65; 0.42–1.02; 0.06

0.64; 0.31–1.30; 0.22

Model 1

1

0.66; 0.42–1.04; 0.07

0.67; 0.33–1.37; 0.27

Model 2

1

0.65; 0.41–1.02; 0.06

0.68; 0.33–1.38; 0.28

Model 3

1

0.65; 0.41–1.03; 0.06

0.66; 0.32–1.35; 0.26

CV risk score ≥10

Number

362

306

93

Incident CV events

44

26

8

 

HR

HR; 95 % CI; p

HR; 95 % CI; p

Crude

1

0.70; 0.43–1.14; 0.14

0.71; 0.33–1.50; 0.37

Model 1

1

0.71; 0.44–1.16; 0.17

0.76; 0.35–1.63; 0.48

Model 2

1

0.69; 0.42–1.13; 0.14

0.72; 0.33–1.55; 0.40

Model 3

1

0.71; 0.43–1.16; 0.18

0.68; 0.31–1.45; 0.32

CV mortality

28

18

4

 

HR

HR; 95 % CI; p

HR; 95 % CI; p

Crude

1

0.74; 0.41–1.35; 0.33

0.54; 0.19–1.54; 0.25

Model 1

1

0.73; 0.40–1.33; 0.30

0.81; 0.28–2.34; 0.70

Model 2

1

0.79; 0.43–1.44; 0.44

0.81; 0.28–2.37; 0.70

Model 3

1

0.70; 0.37–1.29; 0.26

0.76; 0.26–2.20; 0.61

All-cause mortality

66

51

13

 

HR

HR; 95 % CI; p

HR; 95 % CI; p

Crude

1

0.90; 0.62–1.29; 0.56

0.74; 0.41–1.35; 0.33

Model 1

1

0.89; 0.62–1.28; 0.54

1.06; 0.58–1.94; 0.84

Model 2

1

0.90; 0.62–1.31; 0.60

1.02; 0.55–1.88; 0.95

Model 3

1

0.88; 0.61–1.29; 0.52

1.00; 0.54–1.83; 0.99

  1. Model 1: adjusted for age, sex, BMI
  2. Model 2: adjusted for age, sex, BMI, smoking habits, systolic and diastolic blood pressure, fasting glucose, total and HDL-cholesterol
  3. Model 3: adjusted for age, sex, BMI, smoking habits, systolic and diastolic blood pressure, fasting glucose, total and HDL-cholesterol, rural area, exercise level, baseline CV risk score and education
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Journal of Translational Medicine

ISSN: 1479-5876

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