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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy

Fig. 8

AMP-activated protein kinase (AMPK) phosphorylation and the interaction between the B cell lymphoma 2 (Bcl-2) and Beclin 1 proteins in the heart of rats in the control, diabetes mellitus (DM), and diabetes mellitus + trimetazidine (DM + TMZ) groups. a shows a western blot analysis of phosphorylated AMPK (p-AMPK)/total AMPK (t-AMPK), while b shows coimmunoprecipitation analysis of combination of the B-cell lymphoma 2 (Bcl-2) protein and the protein Beclin 1. Data are mean ± SEM; AMP, adenosine monophosphate. *p < 0.05 compared with control group; and # p < 0.05 compared with diabetes group

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