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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: miR-29b and miR-198 overexpression in CD8+ T cells of renal cell carcinoma patients down-modulates JAK3 and MCL-1 leading to immune dysfunction

Fig. 7

Transfection with specific Anti-hsa-miR inhibitors upregulate MCL-1 and JAK3 protein expression and rescues the cells from apoptosis. Annexin V/PI assays in PBMCs after 48 h of transfection with Anti-hsa-miR-198 or Anti-hsa-miR-29b. Apoptotic cells were calculated as the sum of early and late apoptotic cells (a). The results are shown as percentage of apoptotic cells. Data are the average of six independent experiments ±SD, p < 0.01 and §p < 0.03 versus SCR (b)

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