|
Parameter
|
Gene
|
SNP ID
|
Bootstrap p value (95 % CI)
|
|---|
|
MCR
|
FAS
|
rs2234978
|
0.138 (0.000–0.605)
|
|
CCR
|
FAS
|
rs2234978
|
0.187 (0.000–0.727)
|
|
MMR
|
FASLG
|
rs763110
|
0.065 (0.000–0.351)
|
|
FAS
|
rs2234978
|
0.178 (0.000–0.762)
|
|
MR4.5
|
FAS
|
rs1800682
|
0.497 (0.053–0.951)
|
|
FAS
|
rs2234767
|
0.050 (0.000–0.221)*
|
|
FAS
|
rs2234978
|
0.073 (0.000–0.345)
|
|
LOR
|
APAF1
|
rs1439123
|
0.142 (0.000–0.749)
|
|
FAS
|
rs2234767
|
0.169 (0.000–0.783)
|
|
TF
|
CASP10
|
rs13006529
|
0.102 (0.000–0.563)
|
|
PFS
|
FASLG
|
rs763110
|
0.365 (0.003–0.992)
|
|
OS
|
CASP10
|
rs13006529
|
0.162 (0.002–0.991)
|
|
FASLG
|
rs763110
|
0.424 (0.017–0.994)
|
-
MCR major cytogenetic response, CCR complete cytogenetic response, MMR major molecular response, MR4.5 complete molecular response, LOR loss of response, TF treatment failure, PFS progression free survival, OS overall survival, HNF4A hepatocyte nuclear factor 4, alpha, APAF1 apoptotic peptidase activating factor 1, FAS Fas cell surface death receptor, FASLG Fas ligand (TNF receptor superfamily member 6)
- * P ≤ 0.05
