Skip to main content

Table 2 Distributions of genotype and allele frequency in healthy controls and patients

From: Polymorphisms in FADS1 and FADS2 alter plasma fatty acids and desaturase levels in type 2 diabetic patients with coronary artery disease

SNP Genotype Healthy controls
(n = 253)
T2D patients
(n = 234)
CAD patients
(n = 200)
T2D &CAD patients (n = 185) HWEa p valueb Additive model, p valuec Dominant model, p valuec
rs174537G>T GG 65 88 58 63 0.56 0.009 0.032 0.027
GT 131 106 90 91
TT 57 40 52 31
rs174616C>T CC 113 104 88 99 0.59 0.383 0.445 0.180
TC 115 109 90 68
TT 25 21 22 18
rs174460C>T TT 151 129 106 112 0.56 0.185 0.136 0.344
TC 91 81 78 56
CC 11 24 16 17
rs174450A>C AA 101 86 82 80 0.46 0.550 0.743 0.589
AC 122 113 96 80
CC 30 35 22 25
  1. aHardy–Weinberg Equilibrium (HWE) was calculated in healthy controls
  2. b p values derived from the Chi square test of allele frequency
  3. c p values derived from the Chi square test of genotype distribution