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Table 2 Comparative product quality (target fraction; mean ± SEM)

From: Automation of cellular therapy product manufacturing: results of a split validation comparing CD34 selection of peripheral blood stem cell apheresis product with a semi-manual vs. an automatic procedure

 

CliniMACS

Prodigy

t test

T-cells/4 × 106 CD34+

926 ± 213

4989 ± 2425

0.171

B-cells/4 × 106 CD34+

2012 ± 1512

7711 ± 6664

0.013

Recovery CD34+

61 ± 5

58 ± 5

0.736

B-cell depletion

9.30−5 ± 1.51−5

3.52−4 ± 6.27−5

0.016

T-cell depletion

1.32−5 ± 1.95−6

5.78−5 ± 8.63−6

0.007