Skip to main content

Advertisement

Table 2 Univariate and Multivariate analysis for survival in higher risk MDS patients treated with decitabine

From: High expression of the human equilibrative nucleoside transporter 1 gene predicts a good response to decitabine in patients with myelodysplastic syndrome

Criterion Univariate P value Multivariate P value HR 95.0 % CI for HR
Hemoglobin (>80 g/L vs ≤80 g/L) 0.010 0.026 2.023 1.177–4.112
Platelet (>50 × 109/L vs ≤50 × 109/L) 0.008 0.022 2.134 1.113–4.091
Bone marrow blasts percentage (5–10/10–20/>20 %) 0.010 0.041 1.522 1.017–2.277
hENT1 expression (high vs low) 0.027 0.031 2.363 1.174–4.757
Age (>60 years vs ≤60 years) 0.796
Gender (male vs female) 0.569
Neutrophils (>1.0 × 109/L vs ≤1.0 × 109/L) 0.212
Karyotype (low/intermediate/high) 0.318
hENT2 expression (high vs low) 0.201
DCK expression (high vs low) 0.203
CDA expression (high vs low) 0.411