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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: High expression of the human equilibrative nucleoside transporter 1 gene predicts a good response to decitabine in patients with myelodysplastic syndrome

Fig. 4

LINE-1 methylation level before and after decitabine treatment in hENT1-siRNA and control SKM-1 cells. a hENT1 mRNA expression in SKM-1 cells transfected with hENT1-siRNA-lentivirus and control lentivirus. b LINE-1 methylation levels changed with different concentrations of decitabine. cf A pyrosequencing assay was used to measure LINE-1 methylation before decitabine treatment in control lentivirus-transfected (c) and hENT1-siRNA cells (d). LINE-1 methylation was also measured after 1 µM decitabine treatment in control (e) and hENT1-siRNA cells (f)

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