Fig. 2From: PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcomaSecondary validation of selected hits discovered in primary screen in LMS cell lines. Treatment of SKLMS1 and STS39 cell lines with four inhibitors using a 10-point, threefold serial dilution, generating EC50 curves ranging from 0.25 to 5000 nM. Cells were incubated for 72 h and cell viability quantified with ATPlite (n = 3)Back to article page