Fig. 7
From: Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation
PRRs mRNA expression and protein levels were induced at exacerbation only. RIG-I (a), MDA5 (b), and TLR3 (c) mRNA were increased exclusively at dsRNA-induced exacerbation. Similarly, protein levels of RIG-I (d), MDA5 (e) and TLR3 (f) were also increased exclusively at exacerbations. Optical density was determined from western blot bands and related to housekeeping protein β-tubulin. Representative blots are shown below the calculated protein levels. The data are presented as mean ± SEM (n = 4–6 mice in each group), ***p < 0.001; **p < 0.01; *p < 0.05 compared to HDM/saline control