Fig. 6
From: Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation
HDM-induced IL-33 protein was further increased at dsRNA-induced exacerbation. IL-33 protein in lung homogenate increased efter HDM challenge alone and was further increased by dsRNA-induced exacerbation (a). Immunohistochemistry showed IL-33 protein tissue occurrence in paraffin sections of the mouse lungs (b) in accord with the protein analysis (representative photos are shown). The data are presented as mean ± SEM (n = 4–6 mice in each group). #p < 0.05 compared to saline control, while *p < 0.05 compared to HDM/saline control