Fig. 5
From: Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation
Upstream TH2-cytokines, IL-33, TSLP and IL-25 were induced at exacerbation. HDM challenges alone caused transiently increased lung tissue mRNA expression of IL-33 (a, left) and TSLP (b, left). dsRNA-induced exacerbation caused further increase in IL-33 (a, right) and TSLP (b, right). However, IL-25 mRNA expression was exclusively induced at exacerbation (c). The data are presented as mean ± SEM (n = 4–6 mice in each group). ##p < 0.01, #p < 0.05 compared to saline control, while ***p < 0.001; **p < 0.01; *p < 0.05 compared to HDM/saline control