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Table 1 Probability (95 % CI) of no metastasis as a function of time

From: Gene expression identifies heterogeneity of metastatic behavior among gastrointestinal stromal tumors

Time (years)

2

4

6

8

HR

A. Two sample subsets defined by the AF-gene set in Fig. 1a (p = 0.003)

Group A, n = 21

NR

NR

NR

NR

Reference group

Group B, n = 39

0.76 (0.63–0.91)

0.60 (0.45–0.81)

0.54 (0.38–0.78)

0.54 (0.38–0.78)

NE

B. Two sample subsets defined by the OVCA-gene set in Fig. 1b (p < 0.001)

Group A, n = 18

NR

0.97 (0.91–1.00)

0.97 (0.91–1.00)

0.97 (0.91–1.00)

Reference group

Group B, n = 42

0.53 (0.34–0.81)

0.28 (0.12–0.67)

0.19 (0.06–0.61)

0.19 (0.06–0.61)

38.7 (5.0–296.9)

C. Two sample subsets defined by the RCC-gene set in Fig. 1c (p = 0.003)

Group A, n = 35

0.94 (0.86–1.00)

0.90 (0.80–1.00)

0.90 (0.80–1.00)

0.90 (0.80–1.00)

Reference group

Group B, n = 25

0.71 (0.55–0.92)

0.56 (0.38–0.81)

0.46 (0.27–0.78)

0.46 (0.27–0.78)

5.4 (1.5–19.3)

D. Two sample subsets defined by the combined gene set in Fig. 1d (p = 0.029)

Group A, n = 14

NR

NR

NR

NR

Reference Group

Group B, n = 46

0.80 (0.69–0.93)

0.66 (0.52–0.84)

0.59 (0.43–0.82)

0.59 (0.43–0.82)

NE

E. Three sample subsets defined by the combined gene set in Fig. 1e (p < 0.001)

Group A, n = 14

NR

NR

NR

NR

Reference Group

Group B1, n = 17

NR

NR

NR

NR

NE

Group B2, n = 29

0.68 (0.53–0.88)

0.47 (0.29–0.74)

0.39 (0.22–0.70)

0.39 (0.22–0.70)

NE

F. Two sample subsets defined by the combined gene set in Fig. 1F (p < 0.001).

Good group, n = 32

NR

NR

NR

NR

Reference Group

Poor group, n = 28

0.67 (0.52–0.87)

0.48 (0.32–0.74)

0.40 (0.23–0.70)

0.40 (0.23–0.70)

NE

  1. NR no recurrence, HR hazard rario, NE hazard ratio can not be estimated when one group has no events