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Table 1 Effects of RU-complexes on growth of various human cancer cells

From: Inhibition of cancer cell growth by ruthenium complexes

Cell linea EC50(µM)b
o-PDA o-BQDI
HCC38 (breast ca. TN) >260 >260
HCC1806 (breast ca. TN) >260 >260
MCF-7 (breast ca. LA) 50 >260
SUM149 (breast ca. TN) 150 >260
HT1080 (osteosarcoma) 130 >260
Raji (lymphoma) 160 >260
Bowes (melanoma) 110 >260
SK-Br-3 (breast ca. Her2+) 50 >260
  1. TN triple-negative, LA luminal A
  2. aCells (2 × 105 cells/well) were treated serially diluted o-PDA or o-BQDI for 48 h. Cell growth was evaluated by colorimetric assays using WST-1 as an indicator. Experiments were repeated three times
  3. bEC50 was calculated from three independent experiments. Standard error was less than 5 % of mean