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Table 1 NBDHEX and MC3181 IC50 values for U-2OS and tumor cell lines of different histotypes

From: c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition

Cell line NBDHEX (μM) MC3181 (μM)
U-2OS 0.9 ± 0.1 1.1 ± 0.1
MM-B1 1.3 ± 0.1 1.6 ± 0.2
MCF-7 1.6 ± 0.1 1.5 ± 0.1
COLO 205 5.3 ± 0.4 6.5 ± 0.2
HT-29 11.0 ± 0.4 15.8 ± 0.8
  1. IC50 values (mean ± SEM, n ≥ 3) after 48 h of treatment with NBDs, as determined from cell viability dose–response curves